Contents

Section I: The Orexin System and Its Role in Regulating Sleep and Wake

Twenty-Three Years of Hypocretins: The “Rosetta Stone” of Sleep/Arousal Circuits

de Lecea, L. 

Interaction between Orexin Neurons and Monoaminergic Systems

Sakurai, T.; Saito, Y.C.; Yanagisawa, M.

Hypocretin/Orexin Receptor Pharmacology and Sleep Phases

Sun, Y.; Tisdale, R.K.; Kilduff, T.S.

Sleep, Orexin and Cognition

Toor, B.; Ray, L.B.; Pozzobon, A.; Fogel, S.M. 

Section II: Cellular and Molecular Dissection of the Orexin System

Subsecond Ensemble Dynamics of Orexin Neurons Link Sensation and Action

Burdakov, D.

Heterogeneity of Hypocretin/Orexin Neurons

Sagi, D.; de Lecea, L.; Appelbaum, L.

Sleep and Metabolism: Implication of Lateral Hypothalamic Neurons

Oesch, L.T.; Adamantidis, A.R.

Cellular Signaling Mechanisms of Hypocretin/Orexin

Kukkonen, J.P.; Turunen, P.M.

Section III: The Orexin System in Sleep Pathology

Sleep Problems in Narcolepsy and the Role of Hypocretin/Orexin Deficiency

Mignot, E.; Zeitzer, J.; Pizza, F.; Plazzi, G.

The Insomnia-Addiction Positive Feedback Loop: Role of the Orexin System

Fragale, J.E.; James, M.H.; Avila, J.A.; Spaeth, A.M.; Aurora, R.N.; Langleben, D.; Aston-Jones, G. 

Causes and Consequences of Chronic Sleep Deficiency and the Role of Orexin

Mullington, J.M.; Cunningham, T.J.; Haack, M.; Yang, H. 

Hypocretin/Orexin, Sleep and Alzheimer’s Disease

Dauvilliers, Y.